2010-2011 AMS-532 Fall-Spring

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Announcement

  • Posted on 09/01 by Trent:
  1. Each participant please update the Wiki as required
  • Posted on 09/10 by Lingling:
  1. Lab rotation is a very important part of this course. It is recommended (required for PhD track) that every new student in Computational Biology track to do three rotations in research groups of his/her special interests. Student must contacted four professors and get their permissions to do a rotation in their group. If you have any questions in regard to choosing a lab, please feel free to talk to professor Rizzo and his students (Trent Balius and Lingling Jiang). Rizzo lab is located in Room 3-129, Math Tower.
  • Posted on 09/15 by Lingling:
  1. Since some students find that the presentation is scheduled close to their AMS535 presentation, I modified the schedule so that people can prepare one at a time.
  • Posted on 11/17 by Lingling:
  1. I set up the rotation presentation schedule. Please prepare for a 15 minutes talk about your first rotation.
  2. We won't have journal club next Wednesday as it will follow a Friday schedule then.

Journal Club Participants, Topics, References, and Schedule

2010 Fall Participant Rotations or Research Group Topic References

NEED TO UPDATE ALL REFERENCES WITH CORRECT CITATIONS USING JACS FORMAT

2010.09.08 Adler, Jeremy -- Network identification Chu LH, Chen BS. Construction of a cancer-perturbed protein-protein interaction network for discovery of apoptosis drug targetsBMC Syst Biol. 2008 Jun 30;2:56.
2010.09.15 Vo, Emily -- GWAS Liu, J. Z.; et al., A versatile gene-based test for genome-wide association studies. Am. J. Hum. Genet. 2010, 87, 139-145.
2010.09.22 Jiang, Lingling -- HIV-gp41 Shi, W. X.; et al., Structural Characterization of HIV gp41 with the Membrane-proximal External Region. J. Bio. Che. 2010, 285, 24290-24298.
2010.09.29 Grinshpun, Boris Maslov Prokaryotic Metabolic Networks - Quadratic Scaling Maslov, S.; et al., Toolbox model of evolution of prokaryotic metabolic networks and their regulation. Proc. Natl. Acad. Sci. 2009, 106, 9743-9748.
2010.10.06 Liu, Jiangyang -- -- --
2010.10.13 Li, Miao Wei Zhu Normalization and DE Evaluation Bullard et al.: Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments. BMC Bioinformatics 2010 11:94.
2010.10.20 Yao, Yuan Wang Enzyme Conformation Wei Min; et al., Two-Dimensional Reaction Free Energy Surfaces of Catalytic Reaction: Effects of Protein Conformational Dynamics on Enzyme Catalysis. J. Phys. Chem. B 2008, 112, 454-466
2010.10.27 Gardin, Justin Michael -- -- --
2010.11.03 Chen, Jia Ruo -- -- --
2010.11.10 Cao, Yiwei Green Protein Design Shannon A. M.; et al., One- and two-body decomposable Poisson-Boltzmann methods for protein design calculations. Protein Sci. 2005, 14, 1293-1304.
2010.11.17 Balius, Trent Rizzo Drug design

Jorgensen W. L., Efficient Drug Lead Discovery and Optimization. Acc. Chem. Res. 2009, 42, (6), 724-733

2010.12.01 Grinshpun, B; Liu, J; Li, M -- rotation presentation --
2010.12.08 Gardin, J; Chen, J; Cao, Y; Yao, Y -- rotation presentation --
2010 Spring Participant Rotations or Research Group Topic References

NEED TO UPDATE ALL REFERENCES WITH CORRECT CITATIONS USING JACS FORMAT

2010.01.27 -- GRD 500 Introduction No discussion.
2010.02.03 -- GRD 500 Scientific Misconduct Discussion.
2010.02.10 -- GRD 500 Mentorship Discussion.
2010.02.17 -- GRD 500 Authorship Discussion.
2010.02.24 -- GRD 500 Plagiarism Discussion.
2010.03.03 -- GRD 500 Managing Data Discussion.
2010.03.10 -- GRD 500 Journalism Discussion.
2010.03.17 -- -- -- Research Rotation Presentations.
2010.03.24 Adler, Jeremy Group Topic Citation.
2010.03.31 -- -- -- Spring Break.
2010.04.07 Au, Loretta Green Neutral Networks Bastolla, et al.; Connectivity of neutral networks, overdispersion and structural conservation in protein evolution. J Mol Evol 2003, 56, 243-254.
2010.04.14 Falk, Adam Rizzo Thermodynamic Integration Steinbrecher, T., Mobley, D.L., Case, D.A.; Nonlinear scaling schemes for Lennard-Jones interactions in free energy calculations. J Chem Phys 2007, 127, 214108.
2010.04.21 Jiang, Lingling Group Topic Citation.
2010.04.28 Vo, Emily Rest Binding Site Evolution Lusk, R. W., Eisen, M. B.; Evolutionary Mirages: Selection on binding site composition creates the illusion of conserved grammars in drosophila enhancers. PLoS Genetics 2010, 6, (1), 1-8.
2010.05.05 Last, First Group Topic Citation.